For the US market, animal health company Zoetis has updated its PCV2 vaccine Fostera PCV using an squalane oil adjuvant.
The adjuvant is commonly known as MetaStim. This is an emulsion used in vaccines to help elicit a humoral and cell-mediated immune response. This preserves the vaccine components so the antigens are released slowly as compared to other types of adjuvants. This release time gives more time for the immune system to develop a response to the virus.
“MetaStim has been used in swine, bovine and equine vaccines for years, including most recently, Fostera PCV MH,” said Darrell Neuberger, DVM, pork technical services, Zoetis. “In fact, Fostera PCV MetaStim is the monovalent porcine circovirus fraction of our one-bottle combination vaccine – Fostera PCV MH. For producers and veterinarians who prefer monovalent vaccines, we want to ensure our PCV vaccine offers the same demonstrated efficacy and safety as the combination vaccine.”
Fostera PCV MH can be used against Porcine Circovirus 2 as well as Mycoplasma hyopneumoniae infections.
Along with the adjuvant update, the updated product also carries the same label claims as the PCV fraction of Fostera PCV MH.
Along with the adjuvant update, the updated product also carries the same label claims as the PCV fraction of Fostera PCV MH. Fostera PCV MetaStim has been demonstrated to aid in preventing viraemia, lymphoid depletion and colonisation of lymphoid tissue caused by PCV2, as well as an aid in reducing PCV2 virus shedding. In addition, the updated product is backed by the industry-leading 23-week duration of immunity against PCV2.
The new product will replace Fostera PCV in the Zoetis portfolio of swine vaccines. Fostera PCV MetaStim is available in 50- and 250-dose vials.